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Jha P, Ramasundarahettige C, Landsman V, Rostron B, Thun M, Anderson RN, et al

[97] study indicated that co-cultured human pulmonary vascular endothelial cells (HPVECs) with different concentrations of CSE (0%, 0.1%, 1% and 10%) significantly promoted cell apoptosis, increased caspase-3 activity, upregulated Bax expression, decreased Bcl-2 expression, and increased expression of the lncRNA MEG3

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A spokesman for the Tax Foundation acknowledged the group receives donations from the tobacco industry, but said the smuggling study was not directly funded by cigarette companies and rejected suggestions it was intended to advance their interests