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Due to the high cost, the dried leaves were largely smoked in small clay pipes, broken examples of which are regularly still found by mudlarks along the banks of the Thames

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Although sporadic cases of the disease were reported in South Asia and Southeast Asia over the following decades, it wasnt until 2007 that the first major outbreak of Zika occurred on the western pacific island complex of Yap (part of the Caroline island group and one of four member states in the Federated States of Micronesia)

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