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doi: 10.3389/fchem.2022.749089 Received 28 July 2021 Accepted 04 May 2022 Published 01 June 2022 Volume 10 - 2022 Edited by Trevor Mischki, Health Canada, Canada Reviewed by Di Jiang, Biogen Idec (United States), United States Ivana Kosarac, Health Canada, Canada Ben Blount, Centers for Disease Control and Prevention (CDC), United States Updates Copyright 2022 Jacob, Chan, Cheung, Bello, Yu, StHelen and Benowitz