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2, towards elevated IL-1, G-CSF, IL-1RA, IL-4, MIP1 and IL-8 in the plasma of smokers but only the level of IL-6 was significantly ( p = 0.049) elevated

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These chemicals damage the lungs over time by reducing oxygen intake, and impairing the lungs' ability to clear out toxins and infections

The accompanying Explanatory Statement has further information

Long-term use of high-dose PPIs can cause vitamin B12 deficiency