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In human CRC, a subset of TAM characterized by SPP1 gene expression was highly enriched in cancerous tissue while being largely absent from healthy tissue (69)

showed that the non-catalytic ligand binding site (ligandin site) is in the dimeric cleft of hGSTO1-1 created by largely hydrophobic residues 18

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N., Fielder, T

Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity

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