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How long a B12 shot lasts depends on the form of B12 used in the injection, how severe your deficiency is, and how well your body absorbs the form thats being injected

Micco et al

The MSCs underwent chondrogenic differentiation, followed by analysis of chondrogenic-related gene expression

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DOI: 10.1016/j.archoralbio.2013.03.017 21

Patients who dont have a deficiency but are looking to optimize their B12 levels may utilize weekly or monthly injections depending on their response to treatment