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1 Pharmacological NMDA receptor antagonism dose-dependently lowers body weight but induces hyperthermia
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In brief, HUVECs were lysed in Co-IP buffer containing 20 mM Tris-HCl (pH 7.5), 100 mM NaCl, 0.5 mM EDTA, 0.5% NP-40, 0.5 mM PMSF, and 0.5% protease inhibitor cocktail on ice for 20 min
Overall, the combined model demonstrates the utility of high quality previously published models when constructing a framework to investigate a specific toxicity
The von Hippel-Lindau tumor suppressor protein: new insights into oxygen sensing and cancer
