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References Risk of venous thrombosis with oral versus transdermal estrogen therapy among postmenopausal women PubMed Postmenopausal Estrogen Therapy Route of Administration and Risk of Venous Thromboembolism ACOG The 2022 Hormone Therapy Position Statement of The North American Menopause Society NAMS Smoking, Estradiol Metabolism and Hormone Replacement Therapy PubMed Nicotine, Cotinine, and Anabasine Inhibit Aromatase in Human Trophoblast In Vitro PubMed Transdermal Nicotine for Smoking Cessation in Postmenopausal Women PubMed