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Results in rodent models have shown that exposure to LAN accelerates mammary tumor development, increases estrogenic activity, and reduces circulating melatonin levels 159

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Sleep duration and risk of type 2 diabetes: a meta-analysis of prospective studies

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Enzymes in different pathways appears to be targets of 5-OP toxicity A variety of different enzymes in different pathways were found to be upregulated during 5-OP exposure