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Cigarette butts are the most common form of litter worldwide, with over 6 trillion cigarettes produced each year

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Proc Natl Acad Sci USA 94:1027910284 Vanden Berghe W, De Bosscher K, Boone E, Plaisance S, Haegeman G (1999) The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter