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Varenicline is the most effective monotherapy currently available a Cochrane network meta-analysis found it more than doubled sustained abstinence rates at 6 months follow-up, compared with placebo (risk ratio 2.88, 95% CI 2.403.47)

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This intimate relation is materially evidenced by the similarity (and sometimes identity) of these plants alkaloids with the neurotransmitters of the human brain

Kennedy Jr., and another top health official, Dr