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Additional risk factors for peripheral arterial disease include high blood pressure, atherosclerosis, diabetes, high cholesterol, and being over the age of 60

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The absence of tobacco and nicotine does not eliminate smoke toxins (Tobacco Control, 2008)

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The researchers then compared the lungs of human smokers against those who never smoked, and again, they found a similar trend: Smokers lungs contained 40% to 50% more ACE2 receptors than those of nonsmokers