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the United Kingdom (May 2017)

A randomized, double-blinded study found that using e-cigarettes containing nicotine may impact peripheral and central hemodynamics and arterial stiffness, with negative effects on the cardiovascular system at levels comparable to traditional tobacco cigarettes [30]

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This data indicates a slightly higher tendency for rural smokers to receive professional advice and assistance, with urban smokers showing a greater reliance on counseling

Smoking is a major risk factor for many medical conditions and is responsible for over 480,000 deaths annually in the United States

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