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Studies have shown that certain polyphenols such as oleuropein (from olive leaf/olive oil) or curcumin (turmeric) reduce NF-B and activate antioxidant enzyme pathways (Nrf2)

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Aberrant DNA methylation of promoter CpG islands can promote the development of gastric and colorectal cancers [14]

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Individuals with null genotypes for GSTM1 or GSTT1 (i.e., they lack functional copies of these genes) exhibit a markedly different pharmacokinetic profile