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Considering the specific safety concerns, contraindications (for example, bupropion is contraindicated in patients who have seizures) and comorbidities, the choice of agent is based largely on patient preference after discussion with a clinician [footnote 53]

However, we can break it down into general stages to give you an idea of what to expect: Withdrawal Symptoms : Within the first 24-72 hours after quitting, you'll likely experience chewing tobacco withdrawal symptoms such as irritability, anxiety, and cravings

Abstract Global smoking prevalence remains high, underscoring the need for strategies that complement conventional cessation