Garcia-Echeverria et al (2004) presented a new compound (a pyrrolo[2,3-d] pyrimidine) that although inhibiting the IGF-1R and IR TK equipotently in cell-free systems, exhibited several-fold selectivity for the IGF-1R in a cellular context and reduced the growth of IGF-1R positive fibrosarcomas in vivo
In research, DSIP is sometimes studied in association with the Selank (GABAergic anxiolytic), theEpithalon (activation of telomerase and pineal melatonin), the Semax (nootropic neuropeptide) or the glutathione (antioxidant neuroprotection)
doi: 10.1016/0006-291X(83)91218-4
Typical Concentrations Referenced in Research Literature Published preclinical literature on the individual components provides concentration reference points
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Methods 9, 493498 10.1038/nmeth.1928 [DOI] [PubMed] [Google Scholar] 114.DeFronzo, R.A