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The Yin and Yang of non-neuronal alpha7-nicotinic receptors in inflammation and autoimmunity

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A genome-wide association study (GWAS) involving over 461,000 individuals identified 97 genetic variations linked to mouth ulcers, confirmed in 355,744 participants, with the primary variable rs76830965 near IL12A showing a protective effect

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The number of Parkinsons cases and length of follow-up duration is also limited, making conclusions difficult