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However, conflicting evidence exists, with certain studies reporting no significant associations between SHS and COPD 22,23,24,25,26

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As the category expands, several major brands have emerged offering similar products with different pouch designs, flavors, and nicotine strengths

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Mortality-based calculations remain relatively inaccurate as they are subject to a large number of confounders that would have to be properly assessed both from air pollution and tobacco-smoking perspectives and would require a considerable amount of work to be quantified

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