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The recognised reasons above, particularly the shift in potassium and the body adjusting to corrected levels, explain the symptoms without needing a detox theory

Metformin, commonly prescribed for type 2 diabetes, is known to reduce B12 absorption over time, as highlighted in MHRA safety updates

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In studies examining muscle regeneration following injury, NNMT inhibition promoted stem cell activation and improved healing outcomes

Researchers studying metabolic dysfunction in adipose tissue have identified NNMT as one of the most consistently upregulated enzymes in obese white fat, making it a high-confidence therapeutic target for metabolic intervention

Soffer shares more advice about vitamin B12