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The demographic, health behavioral, and clinical characteristics of the study population are summarized in Table 1

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The pixel resolution for SI data set images was set to 256 256 pixels

doi: 10.1007/s00431-015-2491-y 88 MartinezF

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Assessment of other subjective effects included parameters of PE: positive PE [AUEC for positive PE from 5 to 240 min after the start of product use (AUEC PEpos 5-240 ) and maximum positive PE after the start of product use (E max PEpos )], and negative PE [AUEC for negative PE from 5 to 240 min after the start of product use (AUEC PEneg 5-240 ) and maximum positive PE after the start of product use (E max PEneg )]