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Elderly patients may be more sensitive to the medications effects and may require slower titration or lower maintenance doses, particularly if they have reduced renal function or are at higher risk for dehydration from gastrointestinal adverse effects

Inflammation Control as a Prerequisite for Tissue Quality KPV has demonstrated potent suppression of inflammatory mediators such as TNF- and IL-6, which are implicated in connective tissue degradation, impaired regeneration, gut barrier dysfunction, and inflammatory contributions to skin aging

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Some researchers prefer to add more water (3-5 mL) to create a more dilute solution that requires a larger, easier-to-measure draw