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doi:10.1073/pnas.1801889115

With continuous supplementation over 28 days, the maximum plasma concentration and total exposure to UA increase in a dose-dependent manner (7)

Molecular mechanisms and potential clinical significance of S -glutathionylation

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Inflammatory or disuse conditions suppress this anabolic signaling and activate proteolytic systems including the ubiquitin-proteasome system (UPS), autophagy-lysosome pathway (ALP), calpains, and caspase-3 (Smuder et al., 2018)

They essentially provide a structural scaffold while promoting cellular repair