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The C max and AUC values observed from use of the nicotine gum are lower than several reported values from previous PK studies with nicotine gum 35,36,37,38

In this situation, wastewater surveillance may be better used for presence/absence monitoring, for example, as an early warning system for the presence of infection in specific catchments, as opposed to quantitative estimation 39

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The remaining lifetime costs included $276,000 for health-care expenses, $7,800 for higher home-insurance premiums, and $703,000 in lost income attributed to smoking-related issues