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Debt deflation: Excess private debt created a dangerous condition where no one wanted to spend, causing deflation and economic weakening

Eventually, this can lead to habit, reduced expression of receptors, higher use, and eventually, dependence

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Somewhat ironically, the best evidence for the effects of nicotine itself come from use of a particular form of tobacco called snus

"So, we know too that people who are younger and take up smoking will have a more difficult time quitting, because they smoke for a longer period of time as well," Warren says

The Great American Smokeout, presented by the American Cancer Society, is Thursday, November 20, 2025