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In one report, people who used e-cigarettes and people who smoked combustible cigarettes had greater increases in blood pressure, heart rate and blood vessel constriction, immediately after vaping or smoking, compared to people who did not use any nicotine

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We also found that lung endothelial damage after switching from cigarettes to IQOS did not match the efficiency by which cessation of cigarette exposure reduced it

To keep the device compact while still allowing the user to finish all the e-liquid, manufacturers include a rechargeable battery that can be powered up via a standard USB-C or Micro-USB cable.