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The available historical data is presented clearly and concisely

Snus is made from dehydrated nicotine with various additives and flavors, as well as tobacco

The disparate results in different studies may have arisen from analytical challenges in measuring 8-oxodG without artifactual oxidation of normal dG during sample processing and analysis, high background levels of this lesion in cellular DNA, multi-source nature of 8-oxodG in biospecimens (endogenous and exogenous), different methodologies used, conditions and time of sample collection, inter- and intra-individual variations in subjects metabolic capacity, DNA repair activity, or antioxidant defenses, and various confounding factors [23, 138, 150, 151]

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64 is a vitola that measures 6 1/4 x 64

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