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6 Conclusion In conclusion, oxidative stress is involved in AD pathophysiology, therefore there is a strong preclinical rationale to incorporate antioxidative agents, as adjuvant treatment, in the AD pharmacopeia
In animals exhibiting behavioral signs of tinnitus, an early, frequency-specific increase in the spontaneous firing rates of neurons in the DCN has been observed, 75 interpreted as a compensatory mechanism for reduced input from auditory nerve fibers originating in the cochlea
They work by scavenging free radicals and reducing oxidative stress, thereby mitigating the risk of conditions such as heart disease, cancer, and neurodegenerative disorders
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