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Target cholesterol levels also differ based on age and gender

So it is usually sourced from Seco leaves

One exception to this is for people with an autoimmune condition such as rheumatoid arthritis or inflammatory bowel disease

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A meta-analysis of over 100 trials concluded that varenicline was just over twice as effective as nicotine replacement therapies and bupropion in helping patients quit (Mills EJ et al, Harm Reduct J 2009;6:25)