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10.1038/518466a Nature 116 ShettyA

Protein arginine methylation, catalyzed by protein arginine methyltransferases (PRMTs), is a prevalent type of post-translational modification that plays a role in various physiological processes, such as cell proliferation, tumorigenesis, and tumor development (10)

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A recent paper [12] reported the use of a more sophisticated gradient that avoided the need for the subsequent elutriation