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However, the precise mechanisms by which NLRP3 is activated in response to monosodium urate crystals remain incompletely understood

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As many psychotropic drugs, including diazepam, haloperidol, olanzapine, clozapine, flufenazine and mirtazapine, are also metabolised by induction of CYP1A2, smoking reduces the blood levels and effectiveness of these drugs

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