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FEBS Letters 238(2):343-346. [doi.org]

Retatrutide achieved up to 24.2% body weight reduction over 48 weeks in the Phase 2 trial published in the New England Journal of Medicine , which involved adults with obesity but without diabetes

The copper chelator tetrathiomolybdate, which blocks the copper-dependent catalytic activity of LOX, is presently undergoing a phase II study (NCT00195091) involving patients with breast cancer at moderate to high risk of recurrence

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