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In addition, PINK1 can phosphorylate the Ser65 site of ubiquitin like (UBL) domain, activate the E3 ligase activity of Parkin and promote the recruitment of Parkin in the outer membrane of mitochondria [144, 145]

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[77] Other studies have found that advertisements, which are high in sensation valued, based on their "ability to elicit sensory, affective, and arousal responses", [78] are best for getting messages across to youths who are highly susceptible to drug use

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