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Multi-omics results show that ALOX15 is the main mediator of phospholipid peroxidation, acting as an ignition point during the ischemia stage, igniting phospholipid oxidation and promoting cell ferroptosis

10.1080/00207454.2018.1443925 7 AziziV.AllahyariF.HosseiniA

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& Jentsch, S

And that comes essentially from the efficiency of trying to intervene in targets that underlie multiple different pathologies, all of which have big markets