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Fluid retention and edema: During treatment with glucocorticoids and diclofenac, edema and fluid retention have been observed so the formula must be used with caution in patients with a history of decompensation, hypertension or other factors predisposing to fluid retention

Never discontinue tirzepatide without medical guidance, as this may result in deterioration of glycemic control or reversal of weight loss benefits

The SS-31 peptide and other mitochondrial-targeted peptides are being studied for their cardiovascular protective properties

Others experience a gradual, steady trend over several months