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While not "safe," nicotine pouches are one of the least harmful ways to ingest nicotine

[DOI] [PubMed] [Google Scholar] 52.Joe H, Oh JE, Cho YJ, Shin HS

Of course, stopping smoking is one of the best ways to reduce the risk of LES irritation, esophagitis, and GERD

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To further investigate the pharmacological effects of the different nicotine salts, we compared the correlation of the DA signal with the filter and blood nicotine content at a concentration of 60 mg/mL