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Early Uses of California Plant, By Edward K

Physical withdrawal symptoms like cravings, irritability, and insomnia start within 24 hours of the last cigarette and peak around the 2- to 3-day mark

Children interviewed by Human Rights Watch described working, especially in wet conditionsduring or after rainfall or in the morning with a heavy dew on the tobacco leavesand becoming severely nauseous, dizzy or lightheaded

[PubMed: 11086367] Laucht M, Becker K, Frank J, Schmidt MH, Esser G, Treutlein J, Skowronek MH, Schumann G

Of this they say, "when they [are] waxed blacke, ...to be ripe, which is when they are yet greene

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