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Both the effect of smoking on microbiome in CF patients and the possible causal relationship between smoking-induced variations of microbiome, possibly through CTFR dysfunction, and the clinical manifestations of CF, could not be proved

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doi: 10.1371/journal.pone.0012889 36 YinWGhebrehiwetBPeerschkeEI

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This game's popularity is likely due to the fact that it's really easy to learn, requires strategy but also has a dice rolling element that gives it an element of luck, and is highly interactive and involves trading with your opponents