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DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta

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Inclusion criteria were: 1) aged 1839 years (21 in Boston due to minimum age of purchase laws), 2) smoke 5 factory-made filtered cigarettes/day for 1 year, 3) fair or better self-rated physical and mental health, and 4) English-speaking

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