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Currently, 15.7% of the population in Japan smokes regularly, including 25.6% of men and 6.9% of women

This is especially concerning given that low levels of nicotine exposure during adolescence can have a profound impact on neurochemistry and behavior (e.g., decreased cognitive function, enhanced drug reward), which contribute to the development of nicotine dependence, as well as substance use disorders [4, 6]

Proper evaluation of the LV in hypertensive patients includes linear measurements of interventricular septal and posterior wall thickness and internal end-diastolic diameter

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These metrics translate to fewer doctor visits for the same condition, greater mobility, low risk of complications, fewer medically-related work absences and lower healthcare spending overall