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Mol Neurobiol 62 , 64236466 (2025)

Perhaps the most significant change occurred with the passage of the Family Smoking Prevention and Tobacco Control Act (TCA) signed by President Obama in 2009

Continuous product innovation, including advancements in aerosol science, device engineering, and oral nicotine delivery systems, is shifting the industry from a volume-focused cigarette market to a more technology- and science-oriented ecosystem

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