inside-out (arguing that a primary CNS degeneration triggers secondary autoimmune inflammation in an immune-predisposed patient) hypothesis (Sen et al., 2020
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As a naturally occurring chemical, GHRH derives from the hypothalamus, an area of the brain that coordinates the bodily system (i.e., the endocrine system) responsible for controlling just about every important function needed for internal stability growth, energy, metabolism, and reproduction, as well as responses to injury, stress, and mood.4 5 True to its name, GHRH causes the pituitary gland to release growth hormone
The math here is important
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DOI: 10.1038/s41419-017-0147-8