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Cigarette smoking has been linked strongly to the following illnesses: heart disease stroke hypertension (high blood pressure) other diseases of blood vessels (such as poor circulation in the legs) and aortic aneurysms (potentially life-threatening disruptions in the wall of the aorta) respiratory illness, including the following: lung cancer emphysema bronchitis pneumonia cancers, including: lip or mouth pharynx or larynx (voice box) esophagus (food pipe) stomach pancreas kidney urinary bladder cervix ovary peptic ulcer disease burns What Are the Health Risks of Obesity
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Citrullination is not specific for RA, however other rheumatologic diseases with synovitis, including inflammatory osteoarthritis, reactive arthritis, undifferentiated arthritis, gout and even trauma, show the presence of citrullinated proteins [76]
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