Dietary folate deficiencies and drugs that interfere with folate metabolism, eg, methotrexate, an anti-carcinogenic agent that inhibits dihydrofolate reductase, and nitrous dioxide (N 2 O), an anesthetic gas that inhibits methionine synthase activity, lead to accumulations and cellular effluxes of homocysteine, causing increases in circulating homocysteine levels (Ueland and Refsum, 1989)
Glutathione is the bodys most abundant, natural anti-oxidant which is produced in the liver to help us rid our body of toxins
Additionally, extended dexamethasone exposure has been shown to induce degenerative necrosis and inflammatory changes in hepatic tissues in experimental models ( Given the toxicity associated with prolonged glucocorticoid use, there is a growing interest in exploring dietary and botanical interventions to mitigate these adverse effects
[DOI] [PubMed] [Google Scholar] 7.Khoshini R., Dai S.C., Lezcano S., Pimentel M
Process Biochem 42(3):454458 Bachhawat AK, Ganguli D, Kaur J, Kasturia N, Thakur A, Kaur H et al Glutathione production in yeast
Pre-treatment aids in reducing the crystallinity so that the carbohydrate degrading enzymes can access cellulose and hemicellulose and break them down into soluble sugars
