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The 2025 escalation has been driven by numbers the Thai government finds alarming: vaping among 15 to 29 year olds rose from 5.8% in 2019 to 12.2% in 2024, and there have been reports of teenagers hospitalised with lung damage and of adulterated "zombie" vapes spiked with sedatives

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Table 14: Estimated AUC024,ss and Cmax,ss for Intravenous Treatment (1-h infusion) in Pediatric Patients Following a Multiple Dosing Regimen of 10 mg/kg, Three Times Daily * 3 x AUC0-8,ss These values are within the range reported for adults at therapeutic doses

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