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These symptoms result from ongoing, often progressive, airflow obstruction due to irregularities in the airways (bronchitis, bronchiolitis) or alveoli (emphysema) [1]

Nicotine is known to rapidly metabolize into cotinine and OH-Cotinine, indirectly contributing to more heightened ROS accumulation 53,54

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Kaestner believes that the main reason for the difference between his findings and previous research is context

However, at high battery voltages, aldehyde emissions are closer to and could even exceed those generated by cigarettes [41]