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In Fleming's first novel Casino Royale (1953), Bond's cigarette of choice is "a Balkan and Turkish mixture made for him by Morlands of Grosvenor Street." Fleming personally disliked cigars and would use cigar smoke as an image of sadness or cheapness in some of his works

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Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice