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Small amounts of nicotine can be mildly toxic to both humans and animals, but in excessive amounts, nicotine can lead to increased heart rate, vomiting, and in rare cases, can even cause comas and death

Lager, et al., 'No association between moist oral snuff (snus) use and oral cancer: pooled analysis of nine prospective observational studies', Scand

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Nearly 3,300 Seminole Indians live on and off reservations throughout Florida

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The regional secretaries sins were deliberately hidden from rank-and-file anger, but enough was leaked to suggest to party members that all might not be quite right with their immediate superiors