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Alternative products such as e-cigarettes and heated tobacco products have gained increasing market share in recent years 44,45 complicating any estimates of smoking-related burden, as their long-term health risks for exclusive and dual users are still unclear

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Key findings: Current cigarette use was strongly associated with frequent headache Former cigarette use also remained associated Current HTP use showed a modest but significant association The association was weaker for HTPs than cigarettes, but not absent While HTPs are often perceived as less harmful, they still deliver nicotine and other constituents, and may be associated with headache burden