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"This is an important moment for consumer protection," said FDA Commissioner Margaret Hamburg, noting tobacco remains "the leading cause of death and disease in this country." The rules will require manufacturers to report their ingredients to the FDA and obtain its approval

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Furthermore, we separately reported the analysis for smokers and non-smokers to account for smokers preconceptions of current cigarette packs

These substances include cocaine, heroin, and marijuana

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Nicotine, although not directly mutagenic, promotes tumor progression by activating nicotinic acetylcholine receptors (nAChRs) and -adrenergic receptors on gastric cells