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PCP-laced marijuana activates parts of the brain that lead to heightened senses, extreme mood changes, and even delusions or psychosis in high doses

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Vascular endothelial dysfunction is the first step in atherosclerosis and plays an important role in the development, maintenance, and progression of atherosclerosis, resulting in cardiovascular events [5, 6]

however, nicotine dependence levels or smoking cessation outcomes may have changed during the study period

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